Bobby Sebra, Director of Technology Development and Associate Professor at the Icahn Institute of Genomics and Multiscale Biology at Mt Sinai in New York
0:00 New 1000 Genomes Project paper & SVs
9:32 Long read apps - What's new?
17:35 Who is Sema4?
10:25 How will sequencing change in the next 2 years?
If today's guest were a super hero, he'd be High Resolution Sequencing Man.
Bobby Sebra is the Director of Technology Development at the Icahn Institute of Genomics and Multiscale Biology at Mt Sinai in New York. He has the complete arsenal of DNA sequencers in his lab. He specializes in long read applications, and today he goes into several of those spaces, including infectious disease and oncology.
How has sequencing changed since we last had Bobby on a couple years ago, and how does he see it changing in the next two years?
Bobby says the technology hasn't so much changed as the sequencing user has. The user is becoming more savvy, more knowledgeable and familiar with the diversity of options. And the biggest trend has been the uptick in single cell sequencing. Beyond that, Bobby has been surprised that the highest demand for single cell sequencing has been coming from clinicians more than from other scientists.
"I wouldn't have predicted it. The clinical community is excited about seeing it come their way for applications like liquid biopsy and the progressive and prospective surveillance of an individual over time," he says.
Finally, one might think that being located in a city like New York would mean access to the greatest variety and range of data for genomics research. But of course there is better. Bobby and his colleagues have formed a new company they're calling Sema4, to open up the data gates to the rest of the world.