Chia-Lin Wei, Director of Genome Technologies at the Jackson Laboratories
00:00 How important is nanopore sequencing to your work?
10:03 Tackling the structural variation landscape in new ways
16:49 The future of cancer research and diagnostics
20:28 The 4D Nucleome Center
We can all recognize that PacBio has laid down the railroad tracks in the frontier of long read sequencing. What many are asking is just how close on their caboose is Oxford Nanopore? And just what exactly will be the differences between the two technologies?
Chia-Lin Wei is the Director of Genome Technologies at the Jackson Laboratories. When we called her up for today’s interview to talk about how she is using nanopore sequencing, she said, “I’ve been using nanopore for years, why the interest this year by the media?”
Well, there are the milestones of first her own lab’s recent paper out on structural variation which shows nanopore sequencing doing what no other technology can. Then there is the Nature paper out earlier this year demonstrating the sequencing of a human genome using only nanopore technology.
But hey, wait a minute. Aren’t we supposed to be asking the questions?
She chuckles and then gives today’s interview covering her lab's paper and peeking into the future of cancer research and clinical diagnostics. Coming in at 23 minutes, the show ends with her describing the 4D Nucleome Center at JAX.