DNA sequencing


Personalized Medicine with Mike Snyder

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Guest:

Dr. Mike Snyder, Director, Stanford Center for Genomics and Personalized Medicine, Bio and Contact Info

Stanford's Center for Genomics and PM Listen (5:06) Stanford's Center for Genomics and PM

Quality of Data Listen (10:05) Quality of Data

Thousand dollar genome, million dollar interpretation Listen (5:38) Thousand dollar genome, million dollar interpretation

Not just genomics Listen (6:35) Not just genomics

Why back at Stanford Listen (1:27) Why back at Stanford

Future of Personalized Medicine Listen (2:36) Future of Personalized Medicine

Michael Snyder is the Director of the Center of Genomics and Personalized Medicine at Stanford. Dr. Snyder is a leader in the field of functional genomics and proteomics. His laboratory study was the first to perform a large-scale functional genomics project in any organism.

Misha Angrist: "Here is a Human Being"

Guest:

Misha Angrist, Ph D, MFA, Author, "Here is a Human Being: At the Dawn of Personal Genomics"Bio and Contact Info

Listen (3:44) Misha 1: PGP a "microcosm" of our lives

Listen (7:03) Misha 2: Why take part in the PGP?

Listen (2:46) Misha 3: The Role of DTC Companies

Listen (1:15) Misha 4: Why not tell daughters about their risk?

Listen (2:13) Misha 5: "Consenting to uncertainty"

Listen (6:53) Misha 6: Experience with Francis Collins

Listen (0;57) Misha 7: X Prize

Listen (1:14) Misha 8: Impression of Jim Watson

Listen (5:05) Misha 9: George Church "the hero of the book"

Listen (2:19) Misha 10: Finally seeing his genome

Listen (3:32) Misha 11: How far along is the PGP?

Listen (4:11) Misha 12: 80 billion bases is a "metric shitload of data"

Listen (2:26) Misha 13 Detractors to the PGP

Listen (1:35) Misha 14: Genomic Resources

Listen (3:05) Misha 15: Sage Bionetworks

Listen (3:30) Misha 16: Is the PGP for everyone

Known as "PGP4," Misha was the fourth member of the original 10 to volunteer to the Personal Genome Project begun by Dr. George Church at Harvard. He has had his genome sequenced and made publicly available. Misha chronicles his experience with the PGP in his recent book, Here is a Human Being: At the dawn of Personal Genomics. Anyone can go to personalgenomes.org and see that Misha is severely allergic to pollen, ragweed and cats. He takes daily Udo’s Choice Adult Blend of Probiotic, Omega 3 Fatty Acids through fish oil, and Lexapro. He is a white, male with A- blood type, is right hand dominant, and wears prescription glasses for near and farsighted vision. One can also find any number of unique genetic variants that Misha carries, including A481T and R305W, variants of the OCA2, an albinism gene. Misha, however, is not albino. The book also tracks the race to the fastest, cheapest mode of next generation sequencing. Dr. Angrist is an assistant Professor at the Duke University Institute for Genome Sciences and Policy. We are happy to have him to mendelspod to talk about his book and about the issues around the intersection of genomes and society.

Genomes on Facebook? Beyond Sequencing 2011

Who owns our genomic data? This question began a panel discussion titled “When People Share Their Genome on Facebook” at the second annual Beyond Sequencing conference in San Francisco Tuesday. The panel was led by Bio-IT World’s editor-in-chief, Kevin Davies, author of The $1,000 Genome. Another panelist, Dr. Pilar Ossorio, quickly deflected the question saying “it’s not a matter of ownership.” She posed another question, could a representation of one’s genomic data be copyrighted? According to Dr.

Retirement Fail . .

Well, I find myself a little less retired than I expected to be. My intention was to take a good long break before looking for something interesting. It seems, however, that something interesting has found me. I'm doing some work for a Danish startup called BlueSEQ.

Eventful Days of April

April Fools Day

There were some big discoveries in the life sciences on April Fools Day (did you hear about a 24th chromosome being found?). So many, in fact, that we were busy all day doing research. After coming across the following announcement of "The Theome Project" around mid-afternoon, we just decided to head out for a drink and call it a day. We so enjoyed this post over at Genotopia, we’ve invited blogger Nathaniel Comfort to join us here at mendelspod.com:



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